Principal Engineer salary at South San Francisco

The average principal engineer salary at South San Francisco was $263,747 , which is 13 percent higher than the average salary for this job in California, and 144 percent higher than the national average for this job . Principal Engineer salaries at South San Francisco typically range from $251,439 to $276,054 (25th to 75th percentile). The highest reported principal engineer salary was $276,054. There are 2 employees at South San Francisco with the job title principal engineer.