Highest salary at Desoto County in year 2022 was $113,121. Number of employees at Desoto County in year 2022 was 200. Average annual salary was $43,121 and median salary was $41,752. Desoto County average salary is 8 percent lower than USA average and median salary is 4 percent lower than USA median salary. From 2021 to 2022, the average salary of employees at this employer increased 10.8 percent, the median salary increased 10.2 percent.